If Augmentin has not been used before, it is recommended that you first undergo an examination to establish the presence of hypersensitivity to the components of the drug before starting treatment. In addition, special tests should be done to confirm that pathological bacteria are sensitive to amoxicillin. Based on the information received from the laboratory, the doctor determines in what mode and in what form the medication should be used, what possible side reactions may be and how the patient should behave and their appearance.
The minimum therapeutic course lasts five days, the maximum duration is two weeks, after which a thorough study of the body's parameters should be carried out to determine how the tool affected various functions, organs.
Range of activity and pharmacological action
Many gram-positive and gram-negative bacteria are sensitive to the action of Augmentin, among which:
- Staphylococcus aureus, including beta-lactamase producing strains;
- Neisseria, the causative agent of gonorrhea;
- E. coli, including those producing beta-lactamase;
Separately, we note that methicillin-resistant strains of Staphylococcus aureus, which cause dangerous nosocomial infections, are insensitive to Augmentin.
The mechanism of action of Amoxicillin is extremely simple. The antibiotic blocks the synthesis of the cell wall of sensitive microorganisms and thus has a bactericidal effect.
The pharmacological effect in Augmentin has only one active substance of the drug - amoxicillin. Clavulanic acid has no antibacterial effect.
Video about taking the drug
Augmentin is a broad-spectrum antibiotic that belongs to the combined group. It is characterized by good tolerance for the penicillin group, high efficiency against a large number of pathogenic microorganisms. An important advantage is the ability to use it in the treatment of young children..
Indications for use
- acute bacterial sinusitis (with a confirmed diagnosis)
- acute inflammation of the middle ear (acute otitis media)
- exacerbation of chronic bronchitis (with a confirmed diagnosis)
- urinary tract infections (cystitis, pyelonephritis)
- infections of the skin and soft tissues (in particular, cellulite, animal bites, acute abscesses and phlegmon of the maxillofacial region)
- infections of bones and joints (in particular, osteomyelitis)
Formal recommendations for the appropriate use of antibacterial agents should be taken into account..
Hypersensitivity (including to cephalosporins and other beta-lactam antibiotics), infectious mononucleosis (including with the appearance of a measles-like rash), phenylketonuria, episodes of jaundice or impaired liver function as a result of the use of amoxicillin / clavulanic acid in history; CC less than 30 ml / min (for tablets 875 mg / 125 mg). With caution. http://www.drugs.com/uk/augmentin-625-mg-tablets-leaflet.html Pregnancy, lactation, severe liver failure, gastrointestinal diseases (including a history of colitis associated with the use of penicillins), chronic renal failure.